聂开立 Kaili NIE
副教授 Associate Professor
所授课程 Course：生物化工工艺设计 Bioengineering process design
电子邮箱 Email：niekl@mail.buct.edu.cn
办公地点 Bureau：东校区科技大厦西配楼211
研究方向 Research
酶工程与生物催化 Enzymatic Engineering and Bio-catalysis
教育背景
Educational Background
2004 - 2009 北京化工大学 生命科学与技术学院 BUCT-College of Life Science and Technology
- 生物化工工学博士 PhD. of Biochemical Engineering
2001 - 2004 北京化工大学 生命科学与技术学院 BUCT-College of Life Science and Technology
- 生物化工工学硕士 Master of Biochemical Engineering
1997 - 2001 河北工业大学 化学工程学院 Hebei University of Technology, College of Chemical Engineering
- 化学工程工学学士 Bachelor of Chemical Engineering
工作经历
Professional Experience
2016.2 - 今 北京化工大学 Beijing University of Chemical Technology
- 生命科学与技术学院副教授，博导 Associate professor, Doctoral supervisor in College of Life Science and Technology
2011.7 - 2016.2 北京化工大学 Beijing University of Chemical Technology
- 厦门生物产业研究院技术总监 Chief Technology Officer, Xiamen Biological Industry Research Institute
2010.5 - 2011.5 美国纽约州立大学 State University of New York
- 环境科学与森林学院博士后 Postdoctoral fellow, College of Environmental Science and Forest
2009.6 – 2010.5 北京化工大学 Beijing University of Chemical Technology
- 生命科学与技术学院科研助理 Research Assistant, College of Life Science and Technology
学术著作
Academic Work
1. One-step synthesis of 4‐octyl itaconate through the structure control of lipase, Journal of Organic Chemistry, 2021, 86: 7895-7903.
2. The conversion of linoleic acid into hydroxytetrahydrofuran-structured bio-lubricant，Journal of Environmental Management, 2021, 291: 112692.
3. Engineered stable 5-hydroxymethylfurfural oxidase (HMFO) from 8BxHMFO variant of Methylovorus sp. MP688 through B-factor research, Catalysts, 2021, 11(12): 1503.
4. Modification and synthesis of low pour point plant-based lubricants with ionic liquid catalysis，Renewable Energy, 2020, 153: 1320-1329.
5. Synthesis of low pour point bio-aviation fuel from renewable abietic acid，Renewable Energy, 2020, 155: 1042-1050.
6. The highly-stable immobilization of enzymes on a waste mycelium carrier，Journal of Environmental Management, 2020, 271: 111032.
6. A core-shell structured immobilized lipase and its application in high-temperature reactions，Applied Biochemistry and Biotechnology, 2019, 189(3): 774-786.
7. β-cyclodextrin as an additive to improve the thermostability of Yarrowia lipolytica Lipase 2: Experimental and simulation insights，Journal of the Taiwan Institute of Chemical Engineers, 2017, 70: 49-55.
8. Sugar-improved enzymatic synthesis of biodiesel with Yarrowia lipolytica Lipase 2, Energy & Fuels, 2017, 31(6): 6248-6256.
9. Chemo-enzymatic epoxidation of Sapindus mukurossi fatty acids catalyzed with Candida sp. 99-125 lipase in a solvent-free system, Industrial Crops and Products, 2017, 98: 10-18.